FOLLOW-UP

Variable

Base line

One year follow

Two years follow

Three years follow

 

RR

P

RR

P

RR

P

RR

P

Gender

0.823 (0.487-1.390)

0.466

1.200 (0.719-2.001)

0.486

1.250 (0.756-2.068)

0.385

1.189 (0.724-1.954)

0.494

Age (years)

1.086 (1.043-1.131)

<0.001

1.073 (1.034-1.114)

<0.001

1.073 (1.035-1.113)

<0.001

1.073 (1.036-1.112)

<0.001

T2DM Evolution (y)

0.978 (0.908-1.053)

0.555

0.990 (0.921-1.060)

0.772

1.017 (0.950-1.088)

0.630

1.016 (0.951-1.086)

0.637

Heterozygous (D/I)

0.509 (0.302-0.857)

0.011

0.569 (0.342-0.945)

0.029

0.555 (0.337-0.916)

0.021

0.557 (0.340-0.913)

0.020

Homozygous (D/D)

1.742 (1.004-3.025)

0.048

0.648 (0.377-1.114)

0.116

0.595 (0.349-1.015)

0.057

0.602 (0.355-1.022)

0.060

 Homozygous (I/I)

 1.402 (0.639-3.075)

0.399

1.409 (0.652-3.044)

0.383

1.263 (0.568-2.725)

0.551

1.300 (0.609-2.776)

0.498

Table 4: Variables related with DPN presence during follow-up. RR: Relative Risk, CI: confidence interval.