Personal details score 1.What is your name ? 0-3 2.When were you born ? 0-2 3.Who am I? 0-2 Spatial orientation score 4.What country are we in? 0-1 5.In which Italian region are we in? 0-1 6.In which city are we in? 0-1 7.What floor are we at? 0-1 8.Where are you 0-2 Temporal orientation score 9.What year is it? 0-1 10.What season are we in? 0-1 11.What month is it? 0-1 12.What is the date today? 0-1 13.What day of the week is today? 0-1 14.Is it day or night ? 0-2

Table 2: Assessment test of cognitive functions consisting of 14 items, modified version of the Folstein MMSE [32], adapted specially for patients presenting severe AD. An imaginary example of a patient is provided below. Total score, PQ=20 points.