Figure 2: GDPβS induces an increase in excitatory postsynaptic current (EPSC) amplitude but does not affect inhibitory synaptic currents (IPSC) amplitude. A: Representative traces of IPSCs recorded at -30 mV just after breaking into the cell (i.e., the control) and after 10 minutes of recording in the presence of Guanosine 5’-[βthiol]diphophate (GDPβS, 10 minutes GDPβS). B: Data summary histogram showing no significant effect of GDPβS on IPSC amplitude. C: Representative traces of EPSCs recorded at -70 mV just after breaking into the cell (i.e., the control) and after 10 minutes of recording in the presence of GDPβS (10 minutes GDPβS). D: Data summary histogram showing a significant increase in EPSC amplitude by GDPβS. Error bar represent the sem, *** statically significant P<0.001).