Patients with another genetic anomaly of the PMP22 gene
Normal limits of our laboratory
Frequency of abnormal results (%)
Mean ± SD
Mean ± SD
Median nerve (n=35)
Sensory CV (m/s)
37.0 ± 8.6
40.3 ± 6.1
≥ 50
100
Sensory amplitude (μV)
12.7 ± 9.4
7.9 ± 1.5
≥ 15
71
Ulnar nerve (n=35)
Sensory CV (m/s)
38.3 ± 9.4
28.0 ± 24.3
≥ 50
91
Sensory amplitude (μV)
13.1 ± 9.2
6.2 ± 5.4
≥ 15
69
Superficial peroneal nerve (n=32)
Sensory CV (m/s)
35.4 ± 13.0
39.3 ± 6.4
≥ 41
69
Sensory amplitude (μV)
8.1 ± 10.1
2.7 ± 0.6
≥ 8
72
Sural nerve (n=32)
Sensory CV (m/s)
34.2 ± 11.0
41.3 ± 7.4
≥ 40
66
Sensory amplitude (μV)
7.6 ± 9.0
2.3 ± 0.1
≥ 7
53
Abbreviations: HNPP=Hereditary Neuropathy with liability to Pressure Palsies; SD=Standard Deviation; CV=Conduction Velocity; m/s=meter/seconde; ms=milliseconde; mV=millivolt; μV=microvolt.
Table 2: Electrophysiological sensory nerves’ characteristics of the
patients with HNPP due to the 1.5 Mb deletion of the PMP22 gene (n
= 33 half-bodies tested) and due to another mutation or deletion (n =
3 half-bodies tested).
