Non-TBI (n=1847) Isolated-TBI (n=77) p-value
Median age, years 33 (23, 49) 31 (23, 58) 0.739
Male gender, % 75% 74% 0.807
White race, % 54% 57% 0.531
Blunt mechanism, % 71% 80% 0.073
Median arrival GCS 14 (3, 15) 3 (3, 7) <0.001
Median arrival SBP, mmHg 130 (107, 149) 133 (118, 152) 0.063
Median arrival HR, bpm 97 (80, 117) 93 (81, 110) 0.306
Median ISS 16 (18, 25) 24 (16, 29) <0.001
Median platelet count x109/L 240 (193, 292) 231 (206, 299) 0.796
Median aPTT, sec 27.4 (24.7, 30.4) 27.2 (24.7, 29.5) 0.866
Median INR 1.10 (1.02, 1.22) 1.16 (1.08, 1.34) 0.013
Median fibrinogen, mg/dL 274 (224, 329) 232 (183, 322) 0.146
Median r-TEG ACT, sec 113 (105, 128) 121 (105, 128) 0.395
Median r-TEG k-time, min 1.4 (1.1, 1.8) 1.6 (1.2, 1.9) 0.117
Median r-TEG alpha, deg 73 (69, 76) 71 (63, 74) 0.059
Median r-TEG mA, mm 64 (59, 68) 64 (58, 66) 0.139
Median r-TEG LY30,  % 0.7 (0.1, 1.8) 0.7 (0.0, 1.6) 0.230
All continuous values are expressed in medians with interquartile range (25th, 75th); TBI: traumatic brain injury; GCS: Glasgow coma scale; SBP: systolic blood pressure; mmHg: millimeters mercury; HR: heart rate; bpm: beats per minute; ISS: injury severity score; aPTT: activated partial thromboplastin time; INR: international normalized ratio; L: liter; sec: seconds; mg/dL: milligrams per deciliter; r-TEG: rapid thrombelastography; ACT: activated clotting time; mA: maximal amplitude; LY30: lysis 30 minutes after mA achieved; min: minutes; deg: degrees
Table 1: Comparison of demographics, admission physiology and lab values and injury severity among isolated TBI vs. non-TBI patients.