Reference Number of patients Underlying Illness Antiviral Rx Other Rx Outcome
(34) JAMA Neurol 39: 785. 1 Hodgekin’s lymphoma  None Prednisone 65 mg qd Cyclophosphamide (Total duration of all treatment said to be 7 months) Improved mental status and seizures, but residual paraplegia
[4] Ann Neurol 19: 7-14. 2 Hodgekin’s lymphoma and diffuse histiocytic lymphoma None None Both patients died
[35] Biomed Pharmacother 51: 449-54. 2 HIV infection Acyclovir 30 mg/kg qd IV for 1 month Corticosteroids for 1 month Hemiparesis improved in both; patient with retinal necrosis had persistent loss of vision
[36]Dermatology 200: 173-175. 1 large B cell lymphoma Acyclovir IV 10 mg/kg TID for 7 days None Improved
[37] IDSA 35: 330-333. 1 HIV infection Acyclovir 10 mg/kg TID IV for 24 days, followed by Valacyclovir 2 GM po TID for 4 weeks None Improved
[38] NEJM 347: 1500-1503. 1 chronic lymphocytic leukemia Acyclovir 10-15 mg/kg TID IV for 7 days None Improved
[39] Pathology 34: 88-93. 1 HIV infection Acyclovir IV None Died
[19] Neurology 70: 853-60. 3 HIV infection (2 patients) and leukemia (1 patient) Acyclovir IV (dose and duration not specified) None 2 improved; 1 died
[19] Neurology 70: 853-60. 1 HIV infection Acyclovir IV (dose and duration not specified) followed by Famvir 500 mg po TID (duration unknown) None Stabilized
[19] Neurology 70: 853-60. 1 HIV infection Acyclovir IV (dose and duration not specified) followed by Valacyclovir for 4 weeks (dose unknown) None Improved
[19] Neurology 70: 853-60. 3 Lymphoma, “low CD4” of unknown etiology, and chronic lymphocytic leukemia Acyclovir IV (dose and duration not specified) Corticosteroids (po and/or IV) 2 progressed; 1 improved
[19] Neurology 70: 853-60. 3 Rheumatoid arthritis and systemic lupus erythematosus (1 patient with both), CREST syndrome, and HIV infection Acyclovir IV (dose and duration not specified) Later addition of corticosteroids (plus one patient received acetylsalicylic acid) 2 improved; 1 stabilized after addition of corticosteroids
[40] Rev Neurol 164: 61-71. 3 Osteosarcoma, heart/lung transplant, and systemic lupus erythematosus Acyclovir 30mg/kg qd IV (duration not specified) None Improved
[41] CID 48: 372-373. 1 HIV infection Acyclovir IV (dose and duration not specified) Corticosteroids Died
[42] J Int Assoc Physicians AIDS Care 10: 144-145. 1 HIV infection Acyclovir 10 mg/kg TID IV for 10 days None Improved
Table 1: Reported treatments for VZV vasculopathy in immunocompromised patients