Figure 1: The effect of ischemic duration of myogenic responses and filamentous (F-) actin content of middle cerebral arteries (MCA). (A) Myogenic tone development in MCA exposed to different periods of ischemia, all with 24 hours of reperfusion: sham-operated control (n=6) and 15 (n=6), 30 (n=7), and 120 minutes (n=8) of ischemia. **P<0.01 versus control. (B) F-actin content in the same arteries shown in (A). Average F-actin content determined by fluorescence intensity of each group of ischemic arteries. **P<0.01 versus control.