Figure 2: Disease scores of MOG-induced animals with established EAE disease and treated with vehicle (saline) or 10 mg/kg OGF for 40 days post disease onset. Mice were observed daily by two individuals, with one masked to the treatment group; behavioral scale ranged from 0-10 (death). Significantly different from EAE +vehicle mice at p<0.05 (*), p<0.01 (**), and p<0.001 (***). (Adapted from Campbell et al., [37])