Figure 3: An axial section of FA (A and B), T2-FLAIR (C) and CBV (D and E) showing the registration results. A set of red tracks are the outlines of the brain and ventricles obtained from the T2- FLAIR image (C), which served as the target image during the registration. The mismatch between the outlines and the original FA (A) or CBV (D) illustrated a severe distortion, whereas a nice match between the outlines and the transformed FA (B) or CBV (E) demonstrated that the distortion was well corrected after the registration.