Figure 1: Serial changes in prefrontal-to-frontal lobe volume ratio in patients with BCECTS (A), CSWS (B), FLE (C) and control subjects. (A) scatter plots for BCECTS patients with cognitive/behavioral problems (longer seizure and abnormal EEG periods; closed squares, shorter seizure and abnormal EEG periods; closed triangles) and age-matched control subjects (open diamonds). (B) scatter plots for CSWS patients with longer seizure durations and CSWS periods (closed circles/squares/ triangles), with shorter seizure durations and CSWS periods (open squares/triangles), and age-matched controls (open diamonds). (C) scatter plots for FLE patients with cognitive/behavioral problems (longer seizure periods; closed squares, shorter seizure periods; closed triangles) and control subjects (open diamonds). BCECTS, benign childhood epilepsy with centrotemporal spikes; CSWS, epilepsy with continuous spikes and waves during slow sleep; FLE, frontal lobe epilepsy.