Gene

SNP ID

Location

Major/Minor allele

Minor Allele Frequency

Association Results

Responder

Non-responder

Allelic OR (95%CI)

Allelic p-value

Corrected p-value*

CFH

rs800292

Exon 2 (I62V)

G/A

0.22

0.29

1.47 (0.71-3.03)

0.3

0.34

CFH

rs1061170

Exon 9 (Y402H)

T/C

0.13

0.02

7.69 (1.59-11.11)

0.026

0.026

CFH

rs1410996

Intron 14

C/T

0.25

0.42

2.17 (1.10-4.17)

0.024

0.032

*Corrections were performed with permutation test SNP: single nucleotide polymorphism, CFH: complement factor H, OR: odds ratio, CI: coefficient interval
Table 2: Summary of single-SNP association analysis with the resopnse to photodynamic therapy in polypoidal choroidal vasculopathy.