Lid Debris (collarettes, clumps/strands) – upper and lower eyelids
(0)      Normal:              Clear eyelid margin

(1)      Mild:                   Occasional fragment, 1-5 collarettes

(2)      Moderate:          Few fragments, 6-20 collarettes
(3)      Severe:              Many fragments, 21-40 collarettes
(4)      Very severe:      Clumps/strands, >40 collarettes
Eyelid Margin Erythema (lower eyelid)
(0)      Normal:              Normal age-related redness and vasculature.
(1)      Mild:                   Slightly dilated blood vessels; vessels colored pink; present in the middle 2/3 section                                      of the lower eyelid margin.
(2)      Moderate:          More apparent dilation of blood vessels; vessel color more intense, whole margin of                                      the eyelid is involved.
(3)      Severe:              Increased vascularity of the eyelid margin, numerous and obvious dilated blood                                     vessels, deep red in color, whole margin of the eyelid is involved.
(4)      Very severe:      Clearly increased confluent vascularity of the eyelid margin; large, numerous dilated                                      blood vessels characterized by deep red color, whole margin of the eyelid is involved.
Plugging of the Meibomian Gland (in the middle part of lower lid, n=10)
(0)      Normal:              Clear orifices of meibomian glands in the middle part of lower lid (n=0)
(1)      Mild:                   Less than 1/3 of orifices but at least one contain turbid secretions (n=1-3)
(2)      Moderate:          Between 1/3 and 2/3 of orifices contain turbid secretions (n=4-6)
(3)      Severe:              More than 2/3 of orifices but not all contain turbid secretions (n=7-9)
(4)      Very severe:      All orifices plugged with turbid or coagulated secretions (n=10)
Secretion Expressed from the Meibomian Gland (lower eyelid)
(0)      Normal:              Minimal clear, oily secretion
(1)      Mild:                   Cloudy secretion
(2)      Moderate:          Granular secretion
(3)      Severe:              Paste-like secretion
(4)      Obstructed:       No expressible secretion
Table 2: Investigator-rated Assessment of Blepharitis Signs.