Patients with
asynchronous bilateralization
(n = 3)
Total
(n = 18)
No.
%
No.
%
No.
%
Age at diagnosis
<12 months
3
20
3*
100
6
33.3
>12 months
12
80
-
-
12
66.7
Total
15
100
3
100
18
100
Tumor focality
Unifocal (single)
11
73.3
2
66.7
13
72.2
Multifocal
4
26.7
1**
33.3
5
27.8
Total
15
100
3
100
18
100
Family history
Negative family history
14
93.3
1
33.3
15
83.3
Positive family history
1
6.7
2***
66.7
3
16.7
Total
15
100
3
100
18
100
*A highly significant statistical correlation was reported between age at diagnosis of
less than one year and asynchronous bilateralization of retinoblastoma (P < 0.001)
**A nonsignificant statistical correlation was found between multifocal tumor at
diagnosis and asynchronous bilateralization of retinoblastoma (P > 0.05)
***A statistically significant correlation was reported between positive family history
and asynchronous bilateralization of retinoblastoma (P < 0.05)
Table 1: Correlation between Age at Diagnosis, Tumor Focality, Family History,
and Asynchronous Bilateralization of Retinoblastoma.
