Protein/Marker of Inflammation |
Results of stimulation studies |
Description |
Primary Antibody |
Irrelevant IgG |
Working Concentration |
Manufacturer |
Detection System |
IL-1 beta |
A |
Interleukin-1 beta, produced by activated macrophage, mediates inflammatory response including cellular proliferation, differentiation, and apoptosis |
Mouse monoclonal anti-human IL-1 beta |
Mouse IgG1 |
1 to 200 |
Sigma Aldrich |
AEC; Sigma Aldrich |
CFI |
A |
Complement factor I is a serine protease that inactivates C3b and C4b |
Mouse monoclonal anti-human CFI |
Mouse IgG1 |
1 to 250 |
Lifespan Biosciences |
Vector Blue; Vector Laboratories |
p-Stat3 |
AMD membranes |
Stat3 is an important signalling molecule for cytokines/growth factor receptors. Here we stained for activated Stat3 (Phospho-Stat3 (Tyr705) (D3A7)). STAT3 is part of the JAK/STAT pathway. |
Rabbit monoclonal anti-mouse phospho-Stat3 |
Rabbit IgG |
1 to 100 |
Cell Signaling Technology |
Vector Blue; Vector Laboratories |
CXCL-11 |
AGE |
IFN-inducible T cell α chemoattractant is a member of the C-X-C chemokine family and is expressed in IFN-γ-treated astrocytes, monocytes, keratinocytes,bronchial epithelial cells and neutrophils |
Rabbit polyclonal anti-human CXCL-11 |
Rabbit IgG |
1 to 100 |
Santa Cruz Biotechnology, INC |
AEC; Sigma Aldrich |
CXCL-10 |
Early biomarker of AMD |
CXCL-10 (IP-10) is a member of the C-X-C chemokine family (pro-inflammatory) |
Mouse monoclonal anti-human IP-10 |
Mouse IgG1 |
1 to 100 |
Santa Cruz Biotechnology, INC |
AEC; Sigma Aldrich |
RSAD2 |
A, AGE |
RSAD2 is involved in antiviral defence (against Hep C, cytomegalovirus, and HIV-1) |
Rabbit polyclonal anti-human RSAD2 |
Rabbit IgG |
1 to 100 |
Santa Cruz Biotechnology, INC |
Vector Blue; Vector Laboratories |