F12 Time (month) Drug Content (%)* PH* Viscosity (Pa*s)* Particle Size (nm)* Encapsulating Efficiency (%)*
Initial 0 91.46 7 8.5 70.3 ± 8.2 62.35
25°C 1 91.46 6.9 8 73 ± 16 _____
2 91.3 6.9 8 89 ± 16.1 _____
3 91 7 7.8 81.7 ± 15.2 60.36
40°C 1 91.46 6 7 75 ± 14.9 _____
2 87.39 6 6.8 118.6 ± 15.2 _____
3 88.7 5.8 6.5 115.2 ± 21.8 51.25
*N=3
Table 9: Stability study of betamethasone sodium phosphate nanopartices (F12) at 25ºC and 40ºC.