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Figure 6: Glaucoma-related stressors differentially alter RGC axonal transport and expression of gp130, GFAP and glutamine synthetase in the ganglion cell and nerve fibers of mid retina. Quantification of fluorescent intensity for cholera toxin-β (CTB) uptake/transport and immunolabeling against gp130 (B), GFAP (C) and glutamine synthetase (D) in the ganglion cell and nerve fiber layers of mid-central to mid-peripheral regions of wholemounted retina from young C57, aged C57, young DBA/2 and aged DBA/2 mice . Data is plotted as intensity of CTB or immunolabeling in arbitrary units. Asterisks indicate statistical significance (p < 0.05). |