Thickness (μm) |
Healthy |
DM |
MDR |
Across All Macular Regions |
|
|
|
RNFL |
42.02 ± 2.11 |
41.19 ± 2.19 |
41.38 ± 2.93 |
GCL+IPL |
78.30 ± 4.09 |
7 5.4 1 ± 5.2 3 † |
(-8 %)71 .80 ± 8.22 ‡ |
INL |
35.02 ± 1.60 |
35.74 ± 2.13 |
35.05 ± 2.76 |
OPL |
41.30 ± 2.49 |
(-10%)39.88 ± 5.04 ‡ |
(-13%)36.07 ± 3.45 ‡ |
ONL+IS |
86.41 ± 5.21 |
85.55 ± 7.32 |
88.39 ± 8.21 |
OS |
16.27 ± 3.06 |
(-20%)17.97 ± 2.64 ‡ |
(-11%)14.40 ± 2.20 ‡ |
RPE |
12.71 ± 1.32 |
(-7%)13.78 ± 1.28 ‡ |
12.76 ± 1.09 |
Foveal Region |
|
|
|
RNFL |
8.85 ± 2.37 |
(-30%)11.83 ± 2.45 ‡ |
8.30 ± 2.44 |
GCL+IPL |
55.80 ± 3.87 |
67.58 ± 15.20 |
(+26%)70.26 ± 11.02 ‡ |
INL |
20.93 ± 1.82 |
25.89 ± 4.30 |
(+19%)25.00 ± 4.85 ‡ |
OPL |
61.24 ± 6.83 |
(-27%)53.08 ± 18.22 ‡ |
(-36%)38.97 ± 12.09 ‡ |
ONL+IS |
99.26 ± 6.79 |
97.42 ± 8.92 |
100.35 ± 12.27 |
OS |
18.05 ± 4.03 |
(-17%)19.53 ± 3.14 ‡ |
16.22 ± 2.96 † |
RPE |
12.84 ± 1.72 |
14.06 ± 1.59 † |
13.10 ± 1.32 |
Parafoveal Region |
|
|
|
RNFL |
33.72 ± 1.85 |
(-8%)34.16 ± 1.48 ‡ |
(-7%)31.33 ± 5.23 ‡ |
GCL+IPL |
94.71 ± 5.73 |
(-7%)92.93 ± 6.75 ‡ |
(-8%)86.73 ± 11.2 ‡ |
INL |
39.60 ± 2.17 |
40.49 ± 2.68 |
39.24 ± 3.32 |
OPL |
37.17 ± 2.68 |
38.15 ± 2.54 |
37.07 ± 2.21 |
ONL+IS |
84.89 ± 6.11 |
83.24 ± 8.16 † |
86.85 ± 8.35 |
OS |
14.80 ± 3.58 |
(-24%)16.97 ± 2.99 ‡ |
12.84 ± 2.50 † |
RPE |
11.57 ± 1.59 |
13.08 ± 1.74 † |
12.02 ± 1.64 |
Perifoveal Region |
|
|
|
RNFL |
41.87 ± 2.94 |
(-6%)41.39 ± 2.68 ‡ |
(-8%)38.7 ± 5.47 ‡ |
GCL+IPL |
67.36 ± 4.52 |
64.39 ± 6.07 |
63.89 ± 8.40 † |
INL |
33.00 ± 1.67 |
33.38 ± 1.91 |
32.77 ± 3.12 |
OPL |
31.54 ± 1.38 |
31.86 ± 1.49 |
31.49 ± 2.17 |
ONL+IS |
75.27 ± 4.84 |
74.67 ± 7.01 † |
78.01 ± 6.50 † |
OS |
14.59 ± 2.81 |
(-23%)16.45 ± 2.64 ‡ |
(-13%)12.72 ± 2.31 ‡ |
RPE |
12.54 ± 1.39 |
13.33 ± 1.51 † |
12.44 ± 1.34 |
† 0.001<p<0.05 and ‡ p<0.001 (ANOVA followed by Newman-Keuls post hoc analysis). For comparisons between MDR and healthy eyes (see MDR column); and between
MDR and DM eyes (see DM column). Changes in percentage are indicated at the upper left of each measure
SD: Standard Deviation; MDR: Mild Diabetic Retinopathy; DM: Diabetes Mellitus |