| |
Baseline |
Final |
Difference (n ± SD) |
Difference (%) |
P value (2-tailed) |
| BCVA (ETDRS letters ± SD) |
34.6 ± 15.4 |
40.5 ± 16.3 |
5.9 ± 11.3 |
+ 17.0 |
0.001 |
| 12° retinal sensitivity (dB ± SD) |
6.3 ± 3.6 |
7.9 ± 4.0 |
+1.6 ± 2.1 |
+25.3 |
<0.001 |
| 4° central retinal sensitivity (dB ± SD) |
2.9 ± 3.1 |
4.2 ± 3.8 |
1.3 ± 3.4 |
+46.9 |
0.008 |
| 12° scotoma points (n ± SD) |
9.6 ± 9.3 |
6.6 ± 8.2 |
-3.0 ± 6.8 |
-31.2 |
0.003 |
| 4° scotoma points (n ± SD) |
2.4 ± 2.0 |
1.8 ± 1.9 |
-0.6 ± 1.8 |
-24.6 |
0.025 |
| 2° central retinal fixation stability (% ± SD) |
48.1 ± 28.3 |
58.0 ± 27.0 |
9.9 ± 24.8 |
+20.6 |
0.007 |
| 4° central retinal fixation stability (% ± SD) |
77.5 ± 25.4 |
84.9 ± 19.5 |
7.4 ± 24.6 |
+9.5 |
0.039 |
| Fixation stability (n) |
P1 = 22 (44%)
P2 = 11 (22%)
P3 = 17 (34%)
1.90 ± 0.89 |
P1 = 22 (44%)
P2 = 11 (22%)
P3 = 17 (34%)
2.22 ± 0.81 |
0.32 ± 0.84 |
+16.8 |
0.025 |
| Location fixation (% ± SD) |
36.1 ± 30.7 |
48.1 ± 29.8 |
12.0 ± 28.4 |
+33.2 |
0.004 |
| Location fixation (n) |
P1 = 17 (34%)
P2 = 19 (38%)
P3 = 14 (28%)
1.92 ± 0.77 |
P1 = 9 (18%)
P2 = 26 (52%)
P3 = 15 (30%)
2.12 ± 0.69 |
0.20 ± 0.73 |
+10.4 |
0.039 |
| Foveal thickness (µm ± SD) |
363.7 ± 116.2 |
237.6 ± 111.9 |
-126.1 ± 133.2 |
-34.7 |
< 0.001 |
BCVA: Best Corrected Visual Acuity; SD: Standard Deviation
Fixation stability:
P1 = Point 1, Instable
P2 = Points 2; relatively instable
P3 = Points 3; stable
Location fixation:
P1 = Point 1, predominantly eccentric
P2 = Points 2; poor central
P3 = Points 3; predominantly central