Figure 6: (A) Normal sequence of UBIAD1 near codon 102 detected in an unaffected control is shown for comparison. (B-F) UBAID1 sequencing revealed that the same heterozygous mutation (N102S) in exon 1, resulting from the AAC>AGC nucleotide substitution in five affected patients with SCD (Case 1, 2, 3, 4 and 5).