Baseline (±SEM) 18 months (±SEM) P Value TISNT average 54 ± 2.5 46.5 ± 2.60 <0.05 Inferior average 53.7 ± 3. 43.6 ± 3 <0.05 Superior average 52.3 ± 2 53.2 ± 0.1 NS TISNT SD 17 ± 1.3 15 ± 1.30 NS NFI 36.8 ± 3 44.8 ± 2.8 NS

Table 3: GDx characteristics.