Fungus Voriconazole concentration 1st week 2ndday 1st week 3rd day 1st week 4th day 2ndweek 2ndday 2ndweek 3rd day 2ndweek 4th day 3rd week 2ndday 3rd week 3rd day 3rd week 4th day Candida albicans 1 μg/ml - - - - - - - - - 2 μg/ml - - - - - - - - - 4 μg/ml - - - - - - - - - Aspergillus fumigatus 1 μg/ml - - - - - - - - - 2 μg/ml - - - - - - - - - 4 μg/ml - - - - - - - - - Alternaria alternata 1 μg/ml - ± + - ± + - ± + 2 μg/ml - - - - - - - - - 4 μg/ml - - - - - - - - - Fusarium solani 1 μg/ml + + + + + + + + + 2 μg/ml ± + + + + + + + + 4 μg/ml - ± + - ± + - + + Fusarium oxysporum 1 μg/ml - ± + - ± + - ± + 2 μg/ml - - - - - - - - ± 4 μg/ml - - - - - - - - -

no growth: - , mild growth: ±, full growth: +

Table 1: Strength of fungal growth accordingly to the drug concentration and the time.