Figure 2: Confocal laser scanning microscopy representative images of oblique sections of sheep and human corneas showing the epithelium, Bowman’s layer, and anterior stroma. (A) Normal appearance of the sub epithelial area in sheep pasturing the Argentinean Pampa (CAPT); (B) numerous hiperreflective dots in the epithelium of sheep’s cornea pasturing the Patagonia region of Argentina (PATG); (C) Normal human cornea (CAPT) shows absence of sub epithelial hyperreflective deposits; (D) CDK grade 1 shows reflective punctiform or dot like deposits at the Bowman´s layer level; (E) CDK grade 2 shows increased density of the hyper reflective punctate deposits in the Bowman´s layer and superficial stroma; (F) CDK grade 3 shows condensation of punctiform hyperreflective deposits and large globular non reflective deposits in the Bowman´s layer and superficial stroma. (C, D, and E) are representative images from CDK patients from PATG region. Original magnification: (400 400 m). Bars = 50 m.