Publication Age (y), sex Phenotype Hb (g/dL) Previous BT VA VF defect Optic disc appearance Treatment Final VA Final VF Follow-up period (months)
[6] 21, M Homozygous B-thal 7.5 Age of 4 y (monthly) CF1m CF0.5m Constriction and superior bitemporalquadrantanopia BE Pale BE BT,RT,C,SX CF2m CF1m Same 96
[5] NA B-thalintermedia NA NA 20/20 20/40 NA Pale BE BT,C,EPO,H 20/20 20/40

NA NA
[4] 13, F B-thal/HbE 7.5 Age of 5 y (every 3 months)

2/60 5/60

Tunnel vision with constriction BE Pale BE BT,RT 6/36 6/24 NA at least 1 week
[7] 21, M B-thalintermedia 8.3 Age of 4 y (intermittent) CF2m HM NA Chronic papilledema BE BT,ACE CF2m CF0.5m NA 13
M: Male; F: Female; y: Years; B-thal: Beta Thalassemia; HbE: Hemoglobin E; Hb: Hemoglobin; BT: Blood Transfusions; VA:Visual Acuity; CF: Finger Count; m: Meter; HM:Hand Motions; VF:Visual Field; BE:Both Eyes; RT:External Radiation; C:Corticosteroids; SX:Partial Excision of Intrasellar Mass (Transphenoidal Approach); EPO:Erythropoietin; H:Hyperbaric oxygen; ACE:Acetazolamide; NA: Not Applicable.
Table 1: Overview of compressive optic neuropathy due to extramedullary hematopoiesis in thalassemia in the current literature.