Hiroshima & Nagasaki |
Minamoto et al. 2004 [14] |
Nakashima et al. 2006 [15] |
Number of subjects |
873 (143 exposed in utero) |
730 |
Mean age at exposure |
8.8 years |
10.5 years (median) |
Mean age at eye examination |
64.8 years |
66.6 years (median) |
Time lag since exposure |
55 years |
55 years |
Eye lens dose |
<0.05 Gy to >2 Gy (84% < 1Gy) |
79% < 1Gy |
Results |
OR/1Gy=1.41 (1.21-1.64) (PSC)
OR/1Gy=1.29 (1.12-1.49) (CC)
Not significant for others |
OR/1Gy=1.44 (PSC)
OR/1Gy=1.3 (CC)
thresholds=0.7 (PSC) and 0.6 Gy(CC) not significantly different from 0
Risk of PSC decreases with increasing age at exposure |
Tchernobyl / Taiwan |
Day et al. 1996 [16]– Children in contaminated territories of Chernobyl |
Chen et al. 2001 [17] – Populations exposed to contaminated building in Taiwan |
Number of subjects |
E=996;NE=791 |
114 |
Mean age at eye examination |
5-17 years |
24.8 years |
Cumulated dose |
- |
161.9 mSv |
Results |
3.6% of PS ocities for E vs. 1.1% for NE (p<0.0005)
Boys 12-17 years ++, absorption of local vegetables |
Significant increase of lens opacities, dose-response relationship for < 20 years subjects (p=0.027) |
