Figure 1: Summary diagram of differentially expressed gene results obtained from a microarray study of hRPE cell response to in vitro stimulation with amyloid beta (0.3 μM, left oval) or advanced glycation endproducts (AGEs, 10 μg/mL, right oval). Amyloid beta and AGEs are two known components of drusen, and results suggest that both induce pro-inflammatory responses, including IFN-γ signaling.