|
Drug |
Genes Responsible For Resistance |
| Streptomycin |
Ribosomal S12 protein (rpsl), 16S rRNA (rrs), Aminoglycoside phosphotransferase gene (strA) |
| Isoniazid |
Catalase-peroxidase enzyme ( kat G), Alkyl hydroperoxidase reductase (ahpC), Oxidative stress regulator (oxy R) |
| Rifampicin |
RNA polymerase (rpoB) |
| Isoniazid-ethionamide |
Mycolic acid synthesis (inhA) |
| Ethambutol |
Arabinosyl transferase (emb A,B,C) |
| Flouroquinolones |
DNA gyrase (gyr A&B) |
|
