Incubation period Total cell counts cells/ml Nisin activityIU/ml Specific nisin activity IU/109 cells/ml Difference rate of specific activity Lactococcus lactis strain F-116, type A Lactococcus lactis strain F-116, type B 1day (24 hours) 1.5 ± 0.2×109 2450 1633 41.8 4.3 ± 0.5×107 2950 68287 2 days 1.4 ± 0.2×109 2450 1713 55.4 3.2 ± 0.4×107 3000 94936 3 days 1.1 ± 0.1×109 3250 3037 28.1 3.3 ± 0.4×107 2800 85365 7 days 1.2 ± 0.1×109 2950 2379 26.7 4.7 ± 0.5×107 3000 63559 10 days 1.3 ± 0.1×109 2450 1870 36.8 3.6 ± 0.4×107 2450 68820 3 months 3 ± 0.3×109 2250 755 40,5 7.2 ± 0.8×107 2200 30556 4,5 months 2.6 ± 0.3×109 2080 784 46.6 6.6±0.7×107 2320 35152 1 year 1.1 ± 0.1×109 2800 2641 18.9 4.9 ± 0.5×107 2450 49796

Table 6: Dynamics of nisin activity in populations of the strain of Lactococcus lactis F-116 under the conditions of a trophic stress.