Incubation period Total cell counts cells/ml Nisin activityIU/ml Specific nisin activity IU/109 cells/ml Difference rate of specific activity Lactococcus lactis strain MSU, type A Lactococcus lactis strain MSU, type B 1day(24 hours) 1.5 ± 0.2×109 3000 2069 25.1 4.7 ± 0.5107 2450 51906 2 days 1.6 ± 0.2×109 3250 2083 35.3 3.4 ± 0.4107 2500 73529 3 days 1.4 ± 0.2×109 3000 2097 27.1 4.4 ± 0.5×107 2500 56818 7 days 1.8 ± 0.2×109 2700 1525 41.7 4.4 ± 0.5×107 2800 63636 10 days 2.1 ± 0.2×109 2750 1322 35.1 5.3 ± 0.6×107 2450 46402 3 months 3.4 ± 0.4×109 2700 794 1/1.5 5.2 ± 0.6×109 2700 524 4,5 months 4.2 ± 0.5×109 2000 480 1.6 2.9 ± 0.3×109 2270 783 1 year 8.8 ± 1×108 2750 3111 1/2.6 2 ± 0.2×109 2750 1375

Table 4: Dynamics of nisin activity in populations of the strain of Lactococcus lactis MSU under the conditions of a trophic stress.