Sexual gametocytes gene |
Gene ID and Source |
Location on chromosome |
Size of coding regions (bp) |
Protein |
Initiation of gene expression |
Function |
Pfs16 |
PF3D7_0406200
PlasmoDB |
4 |
473bp |
Sexual stage protein |
Subpopulation of schizonts, early rings and stage I |
Not well known [19] |
Pfs25 |
PF3D7_1031000
PlasmoDB |
10 |
674bp |
25 KDa ookinete surface antigen precursor |
Ookinete membrane |
Start the formation of oocyst and a good target antigen for transmission blocking vaccine [33] |
Pfg27 |
PF3D7_1302100
PlasmoDB |
13 |
654bp |
Gamete antigen 27/25 |
Gametocyte cytoplasm |
Maturation of gametocyte and confirmation of RNA binding [7,12] |
Pfs230 |
PF3D7_0209000
PlasmoDB |
2 |
9408bp |
6-cysteine protein |
Stage II gametocytes |
The protein help in adherence of gametes to RBCs [42,46] |
Pfs48/45 |
PF13_0247
NCBI |
13 |
1347bp |
Transmission blocking target antigen precursor |
Gametocyte membrane |
Female macrogametes attach to microgametes with the help of fertile male gametes [22,50] |
Pfg377 |
PF3D7_1250100
PlasmoDB |
12 |
9360bp |
Osmiophilic bodies protein |
Osmiophilic bodies and Stage III |
Formation of osmiophilic bodies, and egression of female gametes [56] |