VAS score (mm) Baseline 4 weeks after amazake intake 8 weeks after amazake intake 12 weeks after amazake intake Sense of abdominal distension 14.0 ± 18.1 2.3 ± 4.5 0.0 ± 0.0 0.0 ± 0.0 Edema 30.3 ± 28.5 28.0 ± 28.1 30.0 ± 34.6 19.0 ± 28.9 Fatigue 25.5 ± 21.2 17.8 ± 18.1 12.5 ± 20.0 9.8 ± 11.3 Muscle cramps 58.0 ± 26.8 15.5 ± 20.4 15.8 ± 20.5 20.5 ± 29.7 Loss of appetite 37.3 ± 26.0 7.3 ± 8.8 17.5 ± 29.9 9.3 ± 10.7 Taste disorder 4.8 ± 9.5 2.5 ± 5.0 7.0 ± 9.1 0.0 ± 0.0 Constipation 5.0 ± 10.0 2.5 ± 5.0 0.0 ± 0.0 0.0 ± 0.0 Diarrhea 15.0 ± 20.3 14.0 ± 20.3 23.5 ± 22.2 6.8 ± 8.6 Vomiting 4.3 ± 8.5 2.8 ± 5.5 0.0 ± 0.0 0.0 ± 0.0 Sleep disorder 24.0 ± 29.7 18.3 ± 29.6 18.3 ± 22.2 0.0 ± 0.0

Table 4: Effects of VAS score.