| Groups |
CK-MB(IU/mg protein) |
LDH(nM/mg protein) |
ALT(mM/mg protein) |
AST (mM/mg protein) |
| Normal (1 ml saline) |
183.84 ± 15.60 |
85.64 ± 5.54 |
425.88 ± 14.25 |
410.35 ± 20.50 |
| Control (ISO, 85 mg/kg) |
66.58 ± 27.44* |
53.25 ± 7.88* |
246.55 ± 25.74* |
205.22 ± 11.74* |
| Astaxanthin (50 mg/kg) + ISO (85 mg/kg) |
105.40 ± 23.80* |
63.65 ± 4.26@ |
318.77 ± 15.60* |
297.19 ± 14.85* |
| Astaxanthin (100 mg/kg) + ISO (85 mg/kg) |
165.66 ± 17.45* |
76.18 ± 5.49* |
410.70 ± 18.47* |
386.29 ± 13.78* |
| Vitamin C (1 g/kg,b.w) + ISO (85 mg/kg) |
115.40 ± 32.44* |
70.37 ± 4.17* |
396.06 ± 22.84* |
367.05 ± 14.27* |
Isoproterenol was given subcutaneously as a single dose of 85 mg/kg.b.w. to 18 h fasted animals. It was given to all groups except the normal one. astaxanthin (50 and
100 mg/kg) were orally given daily for 58 days and the last dose of each was given 1 h before Isoproterenol administration. Activity of LDH as (nM of pyruvate liberated/
min/mg of protein); ALT and AST as (mM of pyruvate formed/min/mg of protein) Values are given as mean ± SD for groups of eight animals each.
* Significantly different from normal group at p<0.01. @ Significantly different from control group at p<0.05. |
