Study |
Psarticipants |
Intervention (dose per day) |
Control |
Study design (Jadad score) |
Duration |
Outcome |
(Country) |
Agerholm-Larsen et al. [37] (Denmark) |
70 overweight/obese participants (18-55 y), ♀ (50) and ♂ (20) |
1. Two strains of S. thermophilus and two strains of L. acidophilus (4.5 × 1010 CFU and 9 × 109 CFU) |
450 mL yoghurt fermented with 2. Delta-acid-lactone (chemically fermented placebo group) And 5. Two placebo pills |
Double-blind RCT (3) |
8 wk |
↔BW, FM and waist-to-hip ratio |
2. Delta-acid-lactone (chemically acidified placebo) |
3. Two strains of S. thermophilus and one strain of L. rhamnosus (3.6 × 1011 CFU and 9 × 1010 CFU) |
4. One strain of E. faecium and two strains of S. thermophilus (2.7 × 1010 CFU and 4.5 × 1011 CFU) In 450 mL yoghurt |
5: Two placebo pills |
Kadooka et al. [38] (Japan) |
87 participants with high BMI and visceral abdominal fat areas (33-63 y), ♀ (28) and ♂ (59) |
L. gasseri SBT2055 (1 × 1011 CFU) In fermented milk |
200 g fermented milk |
Double-blind RCT (3) |
12 wk |
↓Abdominal visceral, subcutaneous and total fat areas |
↓BW, BMI, waist circumference, hip circumference, waist-to-hip ratio, FM and fat percentage |
↔Lean mass |
Kadooka et al. [39] (Japan) |
210 participants with large visceral fat areas (35-60 y), ♀ (105) and ♂(105) |
1.L. gasseri SBT2055 (2 × 109 CFU) |
200 g fermented milk |
Double-blind RCT (3) |
12 wk |
1. and 2. ↓Visceral abdominal fat area, BMI, waist circumference, hip circumference and FM |
2.L. gasseri SBT2055 (2 × 108 CFU) |
↔Lean mass and subcutaneous fat area |
3.Placebo In 200 g fermented milk |
Omar et al. [40] (Canada) |
28 overweight participants (46.3±2.4 y), ♀ (18) and ♂ (10) |
1.L. amylovorus (1.39 × 109 CFU) |
100 g fermented yoghurt With diets of 35 E% fat, 50 E% carbohydrate, 15 E% protein |
Randomized double-blind cross-over (3) |
3 × 43 d with 6 wk wash-out |
↔FM, BW and lean mass |
2.L. fermentum (1.08 × 109 CFU) |
3. Placebo In 100 g fermented yoghurt With diets of 35 E% fat, 50 E% carbohydrate and 15 E% protein |
Jung et al. [41] (Korea) |
57 obese participants, (19-60 y), ♀ (35) and ♂ (22) |
L. gasseri BNR17 (1 × 1010 CFU) In capsules |
Placebo capsules |
Double-blind RCT (3) |
12 wk |
↔BW, BMI, fat percentage, muscle mass, waist circumference, hip circumference, VAT, SAT and DAT |
Sharafedtinov et al. [42] (Russia) |
40 obese participants with hypertension, 30-69 y, ♀ (27) and ♂(13) |
L. plantarum TENSIA DSM 21380 (2.5 × 1010 CFU) In 50 g cheese With LCD |
50 g cheese With LCD |
Double-blind RCT (5) |
3 wk |
↓BMI |
↔BW, muscle mass, and FM |
↑Waist-to-hip ratio |
Lee et al. [43] (Korea) |
50 participants with higher BMI (>25 kg/m2) and waist circumference (>85 cm), 19-65 y, ♀ (64) and ♂ (0) |
S. thermophiles KCTC 11870BP, L. plantarum KCTC 10782BP, L. acidophilus KCTC11906BP, L. rhamnosus KCTC 12202BP, B. lactis KCTC 11904BP, B. longum KCTC 12200BP, and B. breve KCTC 12201BP (1 × 109 viable cells) In capsules With 3 g Bofutsushosan and hypocaloric diet |
Placebo capsules With 3 g Bofutsushosan and hypocaloric diet |
Double-blind RCT (3) |
8 wk |
↔BW, BMI, waist circumference, fat percentage and FM |