Groups Urea (mg/dl) Creatinine (mg/dl) Na (mmol/l) K (mmol/l) Serum MDA (nmol/ml)
Control Negative (G1) 44.333±2.603f 0.55±0.029d 164.67±0.882bc 4.433±0.186de 2.867±0.088e
Control Positive (G2) 154±2.082a 1.8333±0.033a 148.33±3.756a 5.267±0.145a 5.333±0.088a
Gentamicin+  OLE 20 mg/Kg (G3) 94±2.646bc 1.2333±0.120b 145.67±2.333a 5±0.058ab 3.567±0.176cd
Gentamicin+  OLE  40 mg/Kg  (G4) 73±1.732e 0.9333±0.088c 168±1.528c 4.9±0.058abc 3.3±0.116d
Gentamicin+  OLE 80 mg/Kg  (G5) 74.333±2.333de 0.7667±0.088cd 164.67±2.906bc 4.667±0.120bcd 2.9±0.058e
Table 1: Effect of olive leaf extracts (OLE), vitamin E (Vit E), and their combination on serum urea, creatinine, Na, K, and MDA levels in gentamicin induced nephrotoxic rats. Values represented as Mean ± SE, The mean difference is significant (P < 0.05) when compared with the positive control group (gentamicin-induced nephrotoxicity).