Groups Initi (g) Fin. (g) Body weight change (%)
Control Negative (G1) 141±1.528a 147.67±2.33b 4.717±0.587b
Control Positive (G2) 138.67±2.33a 132.67±2.67a -4.332±0.735a
Gentamicin+OLE 20 mg/Kg (G3) 139±2.082a 134±2.08a -3.599±0.054a
Gentamicin+OLE 40 mg/Kg  (G4) 140±1.155a 136.67±1.76a -2.388±0.4899a
Gentamicin+OLE 80 mg/Kg  (G5) 139±1.155a 134.33±1.45a -3.361±0.263a
Gentamicin+OLE 160 mg/Kg  (G6) 139±1a 134±1.53a -3.598±0.825a
Gentamicin+Vit. E (G7) 137±1.73a 133.67±0.88a -2.418±0.611a
Gentamicine OLE 20 mg/Kg+Vit. E (G8) 135.67±1.453a 133.33±0.33a -1.698±1.052a
Gentamicine+OLE 40 mg/Kg+Vit. E (G9) 137.67±1.202a 135.67±2.33a -1.427±2.184a
Table 3: Effect of olive leaf extracts, vitamin E, and their combination on animal body weight and % body weight changes in GS-induced nephrotoxic rats. Values represented as Mean ± SE, The mean difference is significant (P < 0.05) when compared with the positive control group (gentamicin-induced nephrotoxicity).