Cotton pellet-induced granuloma formation Groups (n = 6) Dose (mg/kg/d Transudative weight (mg) Granuloma weight (mg) Granuloma inhibition (%) dry Thymus weight (mg/100 g BW) Control SS 594.35 ± 25.60 156.70 ± 3.30 -- 30.49 ± 2.06 Ibuprofen 100 178.90 ± 15.50 (*) 76.20 ± 2.80 (*) 45.56 33. 24 ± 5.40 Meprednisone 5 165.10 ± 14.85 (*) 55.80 ± 9.00 (*) 57.1 22.61 ± 3.95 (*) Aqueous extract 250 581.50 ± 20.15 144.50 ± 13.25 (*) 7.78 31.50 ± 8.05 500 400.95 ± 15.10 (*) 118.45 ± 6.50 (*) 24.41 30.95 ± 4.50 1000 291.00 ± 14.85 (*) 81.85 ± 12.15 (*) 47.76 28.33 ± 3.20 Arrope 250 593.00 ± 10.25 155.45 ± 12.15 0.8 31.80 ± 4.05 500 592.35 ± 1350 153.50 ± 11.50 2.04 31.15 ± 2.50 1000 585.02 ± 25.25 148.53 ± 10.65 5.21 29.69 ± 7.10

Table 2: Effect of Geoffroea decorticans on cotton pellet-induced granuloma formation in rats. Values are expressed as mean ± S.E.M. (n = 6). TrW: Transudative Weight, GrW: Granuloma Weight, GI: Granuloma Inhibition, BW: Body Weight, TW: Thymus Weight. *Significantly different from the control group, p < 0.05, SS (Saline Solution).