Symbol Accession No. Gene Identity Functional Classification Smoked vs Control Smoked+VitA vs Smoked Smoked+VitA vs Control VitA vs Control
Tp53 NM_030989 Tumor protein p53 Tumor suppressor ¯ . ¯ .
Mdm2 XM_235169 Transformed mouse 3T3 cell double minute 2 Tumor suppressor inhibitor . ¯ . .
E2f1 D63165 E2F transcription factor 1 Transcription factor ­­ . . .
Fos X06769 FBJ murine osteosarcoma viral oncogene homolog Transcription factor ­­ ¯ . ­
Nfkb1 L26267 Nuclear factor of kappa light chain gene enhancer in B-cells 1, p105 Transcription factor ­­ . . .
Ecgf1 NM_001012122 Endothelial cell growth factor 1 Growth factor . ¯ . .
Igf1 NM_178866 Insulin-like growth factor 1 Growth factor . ¯ . .
Icam1 NM_012967 Intercellular adhesion molecule 1 Cell adhesion ­­ ¯ . ­
Vcam1 NM_012889 Vascular cell adhesion molecule 1 Cell adhesion . ¯ . .
Egr1 NM_012551 Early growth response 1 Cell division ­­ ¯ . .
Cdk4 NM_031550 Cyclin-dependent kinase 4 Cell division ­­ . ­­ .
Mmp9 NM_031055 Matrix metalloproteinase 9 Cell division ­­ ¯ . .
Rbp2 NM_012640 Retinol binding protein 2, cellular Vitamin A metabolism . ¯ . .
RoDHII BC062000. Retinol dehydrogenase type II Vitamin A metabolism . ¯ . .
Casp7 NM_022260 Caspase 7 Apoptosis ­­ . ­ ­­
Casp8 NM_022277 Caspase 8 Apoptosis . . . ­­
Table 2: Gene identity and function classification for the statistical significantly expressed genes in the lungs from different groups (P < 0.05). Triplicate arrays were analyzed for each group, and data normalized based on Gapd within individual arrays. Dot represents no change between two compared groups. A ↑ indicates up-regulation and an ↓ indicates down-regulation.