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Figure 2: Migration ability of the glioma cell lines after blocking of the
downstream pathways of the EGFR: PI3K by LY294002 and MEK1 by
PD98059 after irradiation with 0, 2, 5 and 8Gy after 12 hours.
Measurements were made in 4 experiments. Radiation-induced migration was significantly blocked by inhibitors of the downstream pathways of EGFR. |