FF-VMAT Average (SD) FFF-VMAT Average (SD) HT Average (SD)
Global max (Gy) 76.9 (1.4) 76.7 (1.1) 74.4 (0.8)*
PTV6996 D2% (Gy) 75.0 (0.9) 75.1 (0.9) 73.6 (0.9)*
PTV6996 D98% (Gy) 68.8 (0.2) 68.8 (0.3) 69.9 (0.1)*
Conformity index 1.036 1.046 1.167*
Homogeneity index 0.084 0.086 0.051*
Brain stem max (Gy) 42.4 (9.2) 42.3 (9.1) 38.7 (9.6)
Cord max (Gy) 41.9 (1.2) 42.2 (1.2) 38.4 (2.3)*
Rt parotid mean (Gy) 26.7 (6.9) 26.6 (7.1) 24.4 (6.4)
Lt parotid mean (Gy) 27.6 (13.3) 27.8 (13.5) 27.3 (15.5)
Larynx mean (Gy) 44.6 (11.3) 44.6 (11.4) 42.2 (11.6)
Body mean (Gy) 13.8 13.6 15.2
Integral body dose (Joules) 160.6 (35.7) 158.1 (34.7) 172.4 (38.0)
Treatment time (sec) 120 120 290.5*
MU 621 726.3 4053.7*
Table 2: Results of the analysis of the difference in the dosimetric parameters in the planning target volume and organs at risk and delivery efficiency among the three techniques. Asterisks indicate statistical significance (FFF-VMAT vs. HT (p < 0.05)). Numbers in parentheses represent one standard deviation. Abbreviations: FFVMAT: Flattening Filter-Volumetric Modulated Arc Therapy; FFFVMAT: Flattening Filter Free-Volumetric Modulated Arc Therapy; HT: Helical TomoTherapy.