Study [references] Duration study conducted Radiation techniques Sample size (n) Follow up period Locoregional Control Freedom From Distant metastasis Overall survival Kim TH [4] 1981-1997 3DCRT 23 7 years 95.2% NA 90% Chen PV [5] 1973-2001 Conventional;3DCRT 44 7.8 years 93% NA 90% Tubiana M [6] 1943-1965 conventional 55 5 years NA 53% 60.6% MSDS trial [12] 2003-2004 3DCRT 26 2.5 years 97% NA 96% Terezakis SA [13] 1989-2006 3DCRT 76 4 years 72% NA 55% Azrif M [14] 1990-2000 Conventional 3DCRT 49 5.4 years 81.4%   75.7% Keum KC [15] 1990-2005 Conventional;3DCRT 25 10 years 89% NA NA Meadows KM [16] 1999-2000 3DCRT 42 5 years 89% 60% 60% Ford D [17] 1988-2001 Conventional;3DCRT 41 5 years 74% NA 67% Busutti L [18] 1982-1995 Conventional;3DCRT 243 5 years 93.7% 93.7% 93.7% O'Connel ME [19] 1969-1991 conventional 103 4 years 81% NA 27%-85% Kim JH [20] 1979-1986 Conventional with doxorubicin 22 2 years 77% NA NA Brierly J [21] 1958-1998 conventional 70 10 years 84.9% 87.3% 65.7% 3DCRT= Three dimensional conformal Radiation therapy, NA= not available

Table 5: Comparison of locoregional, distant control and overall survival rates in various retrospective and cohort studies using conventional radiation therapy and 3DCRT techniques.