Figure 1: Final comparison of generic brands A, B, HM and/or OPT miniprep (top), gel extraction (middle) and PCR Purification (bottom) protocols. GEN A = Nucleic acid extractions using generic A kits; HM-A = Nucleic acid extractions using generic A spin column with HM buffers; OPT-A = Nucleic acid extractions using generic A spin column with OPT buffers; GEN B = Nucleic acid extractions using generic B kits; HM-B = Nucleic acid extractions using generic B spin column with HM buffers; OPT-A = Nucleic acid extractions using generic B spin column with OPT buffers. 10uL of DNA extracted were mixed with 6x loading dye and loaded on a 1% TAE agarose gel. All DNA concentrations determined using IMPLEN Nanophotometer P330 were signifcantly different between groups in One-Way ANOVA. F (5, 12) = 109, p = 0.000, for miniprep; F (5, 12) = 170.691, p = 0.000, for gel extraction; and F (3, 8) = 1250.141, p = 0.000, for PCR Purification. Please see supplementary data for nanospectrophotometer readings.