Figure 3: Changes in albumin secretion activity of hepatocytes on random mono-culture (open triangles), random co-culture (closed triangles), micropatterned mono-culture (open circles), and micropatterned co-culture (closed circles). Error bars represent SD; *, p < 0.05 compared with the value of random mono-culture; #, p < 0.05 compared with the value of micropatterned monoculture; and +, p < 0.05 compared with the value of random co-culture.