| Predictors |
Subsets |
Patients with endpoint, n/N (%) |
Unadjusted HR (95% CI) |
p value |
| Nano-intervention |
Nano Stent Prox |
2/6 (33.3%) |
1.00 |
NA |
| Nano Pre-dilat |
2/9 (22.2%) |
0.67 (0.44-0.91) |
0.03 |
| Nano No prep |
15/45 (33.3%) |
1.00 (0.77-1.25) |
NS |
| Ferro Stent Prox |
2/7 (28.6%) |
0.86 (0.77-1.04) |
NS |
| Ferro Pre-dilat |
7/11 (63.6%) |
1.91 (1.17-2.15) |
NS |
| Ferro No prep |
18/42 (42.9%) |
1.29 (0.86-1.69) |
NS |
| Stenting proximal to the site of nano-intervention |
Nano Stent Prox |
2/6 (33.3%) |
0.56 (0.05-1.12) |
NS |
| Ferro Stent Prox |
2/7 (28.6%) |
0.48 (0.11-1.05) |
NS |
| Stent Control |
6/10 (60.0%) |
1.00 |
NA |
| Balloon pre-dilatation of the target lesion |
Nano Pre-dilat |
2/9 (22.2%) |
0.44 (0.05-0.90) |
0.03 |
| Ferro Pre-dilat |
7/11 (63.6%) |
1.27 (1.08-1.49) |
0.03 |
| Stent Control |
30/60 (50.0%) |
1.00 |
NA |
| No preparation of the target lesion |
Nano No prep |
15/45 (33.3%) |
0.79 (0.64-1.09) |
NS |
| Ferro No prep |
18/42 (42.9%) |
1.00 |
NA |
| Stent Control |
0 (0%) |
NA |
NA |
| Diabetes |
Nano Stent Prox |
2/2 (100%) |
1.09 (0.32-1.66) |
NS |
| Nano Pre-dilat |
2/2 (100%) |
1.09 (0.32-1.66) |
NS |
| Nano No prep |
4/4 (100%) |
1.09 (0.52-1.10) |
NS |
| Ferro Stent Prox |
6/6 (100%) |
1.09 (0.66-1.55) |
NS |
| Ferro Pre-dilat |
3/3 (100%) |
1.09 (0.35-1.44) |
NS |
| Ferro No prep |
9/10 (90.0%) |
0.98 (0.97-1.01) |
NS |
| Stent Control |
11/12 (91.7%) |
1.00 |
NA |
| Heart failure |
Nano Stent Prox |
2/6 (33.3%) |
1.33 (1.10-1.60) |
0.03 |
| Nano Pre-dilat |
2/9 (22.2%) |
0.89 (0.58-1.13) |
NS |
| Nano No prep |
7/44 (15.9%) |
0.64 (0.46-1.01) |
NS |
| Ferro Stent Prox |
2/7 (28.6%) |
1.14 (0.79-1.35) |
NS |
| Ferro Pre-dilat |
5/11 (45.5%) |
1.82 (1.34-2.26) |
<0.01 |
| Ferro No prep |
9/42 (21.4%) |
0.86 (0.77-0.95) |
0.04 |
| Stent Control |
15/60 (25.0%) |
1.00 |
NA |
| Previous or simultaneous PCI |
Nano Stent Prox |
2/6 (33.3%) |
0.33 (0.28-0.43) |
<0.01 |
| Nano Pre-dilat |
2/2 (100%) |
1.00 (0.65-1.22) |
NS |
| Nano No prep |
0 (0%) |
NA |
NA |
| Ferro Stent Prox |
2/7 (28.6%) |
0.29 (0.20-1.18) |
NS |
| Ferro Pre-dilat |
0 (0%) |
NA |
NA |
| Ferro No prep |
0 (0%) |
NA |
NA |
| Stent Control |
10/10 (100%) |
1.00 |
NA |
| Male |
Nano Stent Prox |
2/2 (100%) |
1.53 (1.16-1.81) |
0.02 |
| Nano Pre-dilat |
2/2 (100%) |
1.53 (1.16-1.81) |
0.02 |
| Nano No prep |
15/41 (36.6%) |
0.56 (0.48-1.12) |
NS |
| Ferro Stent Prox |
1/1 (100%) |
1.53 (1.06-2.00) |
0.04 |
| Ferro Pre-dilat |
1/4 (25.0%) |
0.38 (0.26-1.19) |
NS |
| Ferro No prep |
18/39 (46.2%) |
0.71 (0.48-1.16) |
NS |
| Stent Control |
30/46 (65.2%) |
1.00 |
NA |
| Smoking |
Nano Stent Prox |
2/4 (50.0%) |
1.17 (0.97-1.24) |
NS |
| Nano Pre-dilat |
2/6 (33.3%) |
0.78 (0.51-1.32) |
NS |
| Nano No prep |
14/36 (38.9%) |
0.91 (0.82-0.99) |
0.048 |
| Ferro Stent Prox |
2/4 (50.0%) |
1.17 (0.99-1.32) |
NS |
| Ferro Pre-dilat |
3/6 (50.0%) |
1.17 (1.09-1.22) |
0.03 |
| Ferro No prep |
15/27 (55.6%) |
1.29 (1.21-1.36) |
0.01 |
| Stent Control |
18/42 (42.9%) |
1.00 |
NA |
| Alcohol abuse |
Nano Stent Prox |
2/4 (50.0%) |
0.83 (0.71-0.97) |
0.04 |
| Nano Pre-dilat |
2/5 (40.0%) |
0.67 (0.47-0.93) |
0.04 |
| Nano No prep |
15/20 (75.0%) |
1.25 (0.86-1.66) |
NS |
| Ferro Stent Prox |
2/5 (40.0%) |
0.67 (0.56-0.92) |
0.03 |
| Ferro Pre-dilat |
7/7 (100%) |
1.67 (0.96-2.32) |
NS |
| Ferro No prep |
16/25 (64.0%) |
1.07 (0.65-1.42) |
NS |
| Stent Control |
15/25 (60.0%) |
1.00 |
NA |
| Hypertension |
Nano Stent Prox |
1/6 (16.7%) |
0.30 (0.21-0.79) |
<0.01 |
| Nano Pre-dilat |
1/9 (11.1%) |
0.19 (0.11-0.89) |
0.03 |
| Nano No prep |
4/37 (10.8%) |
0.19 (0.12-0.42) |
<0.01 |
| Ferro Stent Prox |
2/7 (28.6%) |
0.51 (0.29-0.74) |
<0.01 |
| Ferro Pre-dilat |
7/11 (63.6%) |
1.14 (0.71-1.57) |
NS |
| Ferro No prep |
18/31 (58.1%) |
1.04 (0.97-1.06) |
NS |
| Stent Control |
30/54 (55.6%) |
1.00 |
NA |
NS – non-significant (p<0.05), NA – non-available, or non-applicable |
