| Company |
Location |
Founder |
In operation |
Year Founded |
Employment |
Total Proceeds in Millions USD |
IPOs, sale of company, acquisitions of other firms |
| Avidimer |
Ann Arbor, MI |
Baker, James R. |
No |
2003 |
5 |
6.7 |
None |
| Liquidia Technologies |
Morrisville NC |
Desimone, Joseph |
Yes |
2004 |
50 |
63.4 |
None |
| Parallel Solutions, Inc |
Cambridge MA |
Esener, Sadik; Langer, Robert S. |
No |
2001 |
9 |
0.9 |
None |
| Ziva |
San Diego CA |
Esener, Sadik |
No |
2002 |
6 |
0.0 |
None |
| Optical Micro-Machines |
San Diego CA |
Esener, Sadik |
No |
2010 |
1 |
0.0 |
None |
| Leonardo Biosystems |
Houston, TX |
Ferrari, Mauro |
Yes |
2005 |
2 |
1.3 |
None |
| NanoMedical Systems |
Austin, TX |
Ferrari, Mauro |
Yes |
2007 |
9 |
5.0 |
None |
| Lumera Corp |
Bothell WA |
Gambhir, Sanjiv |
No |
2000 |
80 |
60.5 |
IPO $41.7M 05-2004; Acquired by GigOptic 12-2008 |
| Forma Therapeutics |
Watertown MA |
Golub, Todd |
Yes |
2008 |
90 |
124.4 |
Acquired SolMap Pharmaceuticals 10-2008 |
| Foundation Medicine |
Cambridge MA |
Golub, Todd |
Yes |
2009 |
5 |
86.0 |
None |
| H3 Biomedicine |
Cambridge MA |
Golub, Todd |
Yes |
2011 |
30 |
400.0 |
Acquired by Eisai Inc., $200M, 01-2011 |
| Integrated Diagnostics Inc |
Seattle WA |
Heath, James |
Yes |
2009 |
5 |
50.0 |
None |
| Combinent Biomedical Systems |
Lexington, MA |
Langer, Robert S. |
Yes |
2000 |
2 |
12.7 |
None |
| PureTech Ventures |
Boston, MA |
Langer, Robert S. |
Yes |
2000 |
15 |
0.0 |
None |
| Momenta Pharmaceuticals |
Cambridge, MA |
Langer, Robert S. |
Yes |
2001 |
197 |
348.9 |
IPO $34.8M 06-2004; Acquired Sialic Switch assets $51.5M 11-2011 |
| Pervasis Therapeutics |
Cambridge, MA |
Langer, Robert S. |
No |
2003 |
10 |
240.2 |
Acquired by Shire PLC, $200M, 04-2012 |
| Pulmatrix |
Boston, MA |
Langer, Robert S. |
Yes |
2003 |
35 |
53.4 |
None |
| Arsenal Vascular (medical) |
Brookline, MA |
Langer, Robert S. |
Yes |
2005 |
3 |
23.8 |
None |
| InVivo Therapeutics |
Cambridge, MA |
Langer, Robert S. |
Yes |
2005 |
16 |
51.4 |
IPO $17.4M, 02-2012 |
| Living Proof |
Cambridge, MA |
Langer, Robert S. |
Yes |
2005 |
33 |
10.9 |
None |
| BIND Biosciences |
Waltham, MA |
Langer, Robert S. |
Yes |
2006 |
20-49 |
63.6 |
No |
| SemprusBioSciences |
Cambridge, MA |
Langer, Robert S. |
Yes |
2006 |
13 |
54.1 |
Acquired by Teleflex, $30M, 06-2012 |
| T2 Biosystems |
Lexington, MA |
Langer, Robert S. ; Weissleder, Ralph |
Yes |
2006 |
25 |
37.7 |
None |
| Selecta Biosciences |
Watertown, MA |
Langer, Robert S. |
Yes |
2007 |
30 |
55.6 |
None |
| Seventh Sense Biosystems |
Cambridge, MA |
Langer, Robert S. |
Yes |
2008 |
6 |
15.2 |
None |
| TARIS BioMedical |
Lexington, MA |
Langer, Robert S. |
Yes |
2008 |
8 |
30.7 |
None |
| Kala Pharmaceuticals |
Waltham, MA |
Langer, Robert S. |
Yes |
2009 |
5 |
12.2 |
None |
| ModeRNA Therapeutics |
Cambridge, MA |
Langer, Robert S. |
Yes |
2009 |
25 |
0.0 |
None |
| 480 Biomedical |
Watertown, MA |
Langer, Robert S. |
Yes |
2011 |
60 |
20.1 |
None |
| Blend Therapeutics |
Watertown, MA |
Langer, Robert S. |
Yes |
2011 |
6 |
2.8 |
None |
| NanoInk |
Chicago, IL |
Mirkin, Chad A. |
Yes |
2000 |
27 |
77.0 |
None |
| Nanosphere |
Northbrook, IL |
Mirkin, Chad A. |
Yes |
2000 |
51-200 |
267.5 |
IPO $98M 11-2007 |
| Aurasense Therapeutics |
Evanston, IL |
Mirkin, Chad A. |
Yes |
2009 |
15 |
7.9 |
None |
| Molecular Imaging Research |
Ann Arbor MI |
Ross, Brian |
Yes |
2002 |
20 |
32.0 |
Acquired by Charles River, $12.5M, 09-2008 |
| Imbio |
Minneapolis MN |
Ross, Brian |
Yes |
2007 |
1 |
0.0 |
None |
| Oncovance Technologies Inc |
Houston TX |
Scardino, Peter |
No |
2003 |
0 |
0.0 |
None |
| Encapsion/Anterios, Inc. |
New York, NY |
Torchilin, Vladimir P |
Yes |
2006 |
80 |
19.8 |
None |
| Nemucore |
Wellesley, MA |
Torchilin, Vladimir P |
Yes |
2008 |
10 |
0.0 |
None |
| MitoVec Inc. |
Boston, MA |
Torchilin, Vladimir P |
No |
2000 |
5 |
0.0 |
None |
| VisEn Medical |
Boston, MA |
Weissleder, Ralph |
No |
2000 |
11-50 |
58.8 |
Acquired by PerkinElmer, $23M, 08-2010 |
| PixelEXX Systems |
St. Louis, MO |
Wickline, Samuel A. |
Yes |
2008 |
4 |
0.3 |
None |
Number of companies=41
Avg.=1.3 |
|
Number of stars founding firms=14 (45.2%) |
Total=32
Avg.=1.0 per star |
|
Total employment=1025 |
Total=
$2294.8M |
|
|
