Figure 8: (a) Citoesqueletal disorganization caused by Cu-F/TiO2 nanoparticles in tumor cells conditioning cell apoptosis. (b) Representation nanobiocatalyst (Cu/F-TiO2) action in tumor cells, where the numbers from (4) to (9) represent the nanoparticules entry, transportation, entry by the nuclear pores, DNA rupture in hydrogen bonds, Mithocondrial rupture action and apoptosis induction conditioned by lisosomal degradation, respectively.