Histological Findings
1
2
3a
3b
3c
Tumoral necrosis
3
1
1
N
N
Tumoral inflammation
2
1
2
3
1
Macrophages presence
1
1
2
3
1
Lymphocytes presence
1
1
2
3
1
Vessels presence
2
1
2
2
1
Hemorrhage
2
2
1
N
N
Mitosis index
10
7
5
3
1
Nanoparticles
N
3
2
1
1
Peritumoral necrosis
N
1
2
1
N
PeritumoraI inflammation
N
1
3
2
N
Peritumoral macrophages
N
1
2
3
1
Lymphocytes
1
1
2
2
1
Gliosis
1
1
3
3
1
Peritumoral hemorrhage
N
2
N
N
N
Nanoparticles
N
1
2
1
1
Neoplastic cells
N
1
2
N
N
Table 2:
Histopathological findings in the GBM tumor and peritumoral boundary. 1-C6 cells, 2-tumor model used only with TiO
2
, 3a,3b,3c- tumor model used with different copper complexes supported in TiO
2
.