| Name of the IV iron preparation |
Status of registration |
Indications |
Test dose |
Duration of infusion |
Maximum dose in single infusion |
| Ferumoxytol (Feraheme®, AMAG Pharmaceuticals, Inc., USA) |
FDA-approved |
Treatment of iron-deficiency anaemia in adult patients with CKD* |
None |
1 minute |
Maximum dose 510 mg |
| Ferric carboxymaltose (Ferinject®, Vifor Pharma, Glattbrugg, Switzerland) |
Approved in Europe,
FDA-approval is sought |
Treatment of iron-deficiency anaemia |
None |
15 minutes |
Maximum dose 1000 mg.
IV rate is 20 mg/kg |
| Ferrosig® (Sigma Pharmaceuticals, USA) |
Approved in Europe,
and by FDA |
Treatment of iron-deficiency anaemia |
Yes |
120 minutes |
No maximum dose |
| Iron isomaltoside (MonoFer®, Pharmacosmos A/S, Holbaek, Denmark) |
Approved in Europe FDA-approval is sought |
Treatment of iron-deficiency anaemia in adult patients with CKD* |
None |
60 minutes |
No maximum dose
IV rate is 20 mg/kg body weight |
FDA: Food and Drug Administration; CKD: Chronic Kidney Disease