| Defect |
Disorder |
| Adhesion |
Bernard-Soulier syndrome
von Willebrand disease, platelet-type |
| Aggregation |
Glanzmann’s thrombasthenia Congenital afibrinogenemia |
| Cytoskeleton |
Wiscott-Aldrich syndrome
MYH9-related disorders(18) |
| Membrane phospholipids |
Scott syndrome |
| Secretion and: Granule anomalies |
Storage pool deficiency (a, d, ad granules) Quebec platelet disorder (a granules) |
| Signal transduction errors |
Platelet receptor defects
G-protein activation defects
Phosphatidylinositol metabolism defects
Calcium mobilization defects
Protein Phosphorylation defects
Arachadonic acid/thromboxane A2 synthesis defects |
