| Therapeutic Modality |
Dosage/Notes |
Hormonal
Acute presentation
1st generation, combined OCP (e.g. Ovral®) Anti-emetic (e.g. Zofran®) PRN Nausea
Stable presentation
2nd or 3rd generation OCPs
Intrauterine Devices (IUD) (Minera®) |
One tab Ovral® PO q 6hrs until bleeding stops, then ↓dose to one tab q8hr x 3days, then one tab BID X 2days, then 1 tab each day
One tab PO q 12hrs until bleeding diminishes/stops, then continue one tab daily
IUD can now be used in adolescents even with history of Pelvic Inflammatory Diseases. The CuT IUD is not recommended to control Abnormal Uterine Bleeding |
Non-hormonal
Acute presentation
Desmopressin (DDAVP®)
Aminocaproic acid (Amicar®)
Platelet Transfusion
Stable presentation
DDAVP nasal spray (Stimate®) |
0.3mg/kg DDAVP® IV in 30ml of saline in 30min infusion
100 mg/kg Amicar® IV or PO followed by 20mg/kg IV or PO q hr until bleeding is controlled
Reserved for patients w/documented PFDs refractory to pharmacological regimens; pediatric hematologist consult
1.5mg/ml Stimate®, if weight < 50kg: one squirt(150mg) in one nostril; if weight ≥ 50kg:one squirt, both nostrils |
Combined therapies may be indicated:
Acute presentation
OCP+DDAVP®
OCP+Aminocaproic acid (Amicar®) |
Combined dosages of OCPs & DDAVP®
Combined dosages of OCPs & Amicar® |
