| Indication |
Reactions |
Molecular target |
Molecular Mechanism |
| 1 |
mucopolysaccaridosis type II |
red man syndrome |
heparan sulfate |
Golgi associated vesicle biogenesis |
| 2 |
hypogammaglobulinemia |
neutralizing antibodies positive |
dermatan sulfate |
Alternative complement activation |
| 3 |
mucopolysaccaridosis |
infusion site pruritus |
mannose-6-phosphate receptor binding protein 1 |
Initial triggering of complement |
| 4 |
mucopolysaccaridosis type VI |
no reaction on previous exposure to drug |
ferritin heavy chain |
Alpha-defensins |
| 5 |
glycogen storage disease type II |
infusion site erythema |
ferritin light chain |
Localization of the pinch-ilk-parvin complex to focal adhesions |
| 6 |
chronic inflammatory demyelinating polyradiculoneuropathy |
oxygen saturation decreased |
myeloid cell surface antigen cd33 |
Other semaphorin interactions |
| 7 |
alpha-1-antitrypsin deficiency |
blood pressure immeasurable |
globotriaosylceramide |
Arf1 pathway |
| 8 |
immunodeficiency |
anaphylactoid reaction |
serotransferrin |
Pten dependent cell cycle arrest and apoptosis |
| 9 |
immunodeficiency common variable |
sense of oppression |
hemoglobin subunit alpha |
Hiv-1 defeats host-mediated resistance by cem 15 |
| 10 |
mucopolysaccharidosis type I |
blood immunoglobulin g increased |
complement c3 |
Hemoglobins chaperone |
| 11 |
iron deficiency anemia |
incorrect drug administration rate |
complement c4a |
Foxo family signaling |
| 12 |
Fabry's disease |
cyanosis |
complement c4b |
Double stranded ma induced gene expression |
| 13 |
pyodermagangrenosum |
infusion site swelling |
high affinity immunoglobulin gamma fc receptor 1b |
endogenoustlr signaling |
| 14 |
uterine cancer |
type IV hypersensitivity reaction |
low affinity immunoglobulin gamma fc region receptor 2a |
Ikk complex recruitment mediated by rip1 |
| 15 |
head and neck cancer |
suffocation feeling |
low affinity immunoglobulin gamma fc region receptor 2c |
Irak1 recruits ikk complex |
