Figure 1: Overview of the natural functions of antibodies. The figure shows the main functions of therapeutic antibodies. The structure of monoclonal IgG antibody is represented, with the colors indicating heavy chains in rose and the light chains in green. The constant domain is represented in red and the variable domain in green. Abbreviations: VL: Variable domain of the Light chain; VH: Variable domain of the Heavy chain; CL: Constant domain of the Light chain; CH: Constant domain of the Heavy chain; Fc: Constant Fragment; Fab: Antigen Binding Fragment.. Tumor cells are represented in orange, and effector cells of the immune system in blue.